Your browser doesn't support javascript.
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
1.
Acad Radiol ; 29(6): 861-870, 2022 06.
Artículo en Inglés | MEDLINE | ID: covidwho-1704817

RESUMEN

PURPOSE: To assess and correlate pulmonary involvement and outcome of SARS-CoV-2 pneumonia with the degree of coronary plaque burden based on the CAC-DRS classification (Coronary Artery Calcium Data and Reporting System). METHODS: This retrospective study included 142 patients with confirmed SARS-CoV-2 pneumonia (58 ± 16 years; 57 women) who underwent non-contrast CT between January 2020 and August 2021 and were followed up for 129 ± 72 days. One experienced blinded radiologist analyzed CT series for the presence and extent of calcified plaque burden according to the visual and quantitative HU-based CAC-DRS Score. Pulmonary involvement was automatically evaluated with a dedicated software prototype by another two experienced radiologists and expressed as Opacity Score. RESULTS: CAC-DRS Scores derived from visual and quantitative image evaluation correlated well with the Opacity Score (r=0.81, 95% CI 0.76-0.86, and r=0.83, 95% CI 0.77-0.89, respectively; p<0.0001) with higher correlation in severe than in mild stage SARS-CoV-2 pneumonia (p<0.0001). Combined, CAC-DRS and Opacity Scores revealed great potential to discriminate fatal outcomes from a mild course of disease (AUC 0.938, 95% CI 0.89-0.97), and the need for intensive care treatment (AUC 0.801, 95% CI 0.77-0.83). Visual and quantitative CAC-DRS Scores provided independent prognostic information on all-cause mortality (p=0.0016 and p<0.0001, respectively), both in univariate and multivariate analysis. CONCLUSIONS: Coronary plaque burden is strongly correlated to pulmonary involvement, adverse outcome, and death due to respiratory failure in patients with SARS-CoV-2 pneumonia, offering great potential to identify individuals at high risk.


Asunto(s)
COVID-19 , Enfermedad de la Arteria Coronaria , Placa Aterosclerótica , Calcificación Vascular , Calcio , Angiografía Coronaria/métodos , Enfermedad de la Arteria Coronaria/diagnóstico por imagen , Vasos Coronarios/diagnóstico por imagen , Femenino , Humanos , Pulmón , Masculino , Valor Predictivo de las Pruebas , Pronóstico , Estudios Retrospectivos , Medición de Riesgo , Factores de Riesgo , SARS-CoV-2 , Calcificación Vascular/diagnóstico por imagen
2.
Can J Cardiol ; 37(10): 1665-1667, 2021 10.
Artículo en Inglés | MEDLINE | ID: covidwho-1265654

RESUMEN

Vaccination plays an important role in the fight against SARS-CoV-2 to minimie the spread of coronavirus disease 2019 (COVID-19) and its life-threatening complications. Myocarditis has been reported as a possible and rare adverse consequence of different vaccines, and its clinical presentation can range from influenza-like symptoms to acute heart failure. We report a case of a 30-year-old man who presented progressive dyspnea and constrictive retrosternal pain after receiving SARS-CoV-2 vaccine. Cardiac magnetic resonance and laboratory data revealed typical findings of acute myopericarditis.


Asunto(s)
Aspirina/administración & dosificación , Vacuna BNT162 , Bisoprolol/administración & dosificación , COVID-19 , Miocarditis , Prednisolona/administración & dosificación , Antagonistas de Receptores Adrenérgicos beta 1/administración & dosificación , Adulto , Antiinflamatorios/administración & dosificación , Vacuna BNT162/administración & dosificación , Vacuna BNT162/efectos adversos , COVID-19/diagnóstico , COVID-19/prevención & control , Forma MB de la Creatina-Quinasa/sangre , Electrocardiografía/métodos , Humanos , Imagen por Resonancia Cinemagnética/métodos , Masculino , Miocarditis/sangre , Miocarditis/etiología , Miocarditis/fisiopatología , Miocarditis/terapia , SARS-CoV-2 , Resultado del Tratamiento , Troponina I/sangre
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA